The Genozymes Project

Written by Paul Gordon

The BIC provides the Genozymes project
(http://artsandscience.concordia.ca/biology/csfg/projects/#Genozymes)
with /de novo/ assembly and functional annotation of fungal
transcriptomes (using Illumina sequences) in the search for enzymes that
can make biofuel production more efficient. The BIC has developed an
assembly pipeline that provides optimal assembly of both high and low
abundance transcripts by combining the results of multiple clipping and
overlap settings, using multiple assembler programs. The BIC also
provides fungal genome annotation using a combination of transcript
data, protein homology and gene prediction software. In depth
annotation, hierarchical clustering of genes, and comparative genomics
is done using the dedicated hardware of the BIC. The MAGPIE and Bluejay
software used to do the analysis and Web presentation of the genomes
acts as a hub from which other project resources (cloning info,
literature, etc.) can be easily linked.